I demonstrated the ability of my bioinformatic frameworks in the collective analysis of 40 heterogeneous budding yeast datasets, which led to the discovery of a novel module of genes that are consistently anti-correlated with growth and ribosome biogenesis .
I also revealed hypotheses regarding the role the yeast CMR1 gene in DNA metabolism via co-expression analysis .
- Basel Abu-Jamous, Rui Fa, David J. Roberts, and Asoke K. Nandi. “Comprehensive analysis of forty yeast microarray datasets reveals a novel subset of genes (APha-RiB) consistently negatively associated with ribosome biogenesis”. BMC Bioinformatics, 2014, 15: 322, doi: 10.1186/1471-2105-15-322. HIGHLY ACCESSED. View online | Download PDF
- Basel Abu-Jamous, Rui Fa, David J. Roberts, and Asoke K. Nandi. “Yeast gene CMR1/YDL156W is consistently co-expressed with genes participating in DNA-metabolic processes in a variety of stringent clustering experiments”. Journal of the Royal Society Interface, 2013, 10(81): 20120990, doi: 10.1098/rsif.2012.0990. View online | Download PDF